Examination of reactions compensatory mechanism of pulp on rat's pulp-

vessels - on vitalmicroscopic model

The dental pulp is covered by a rigid hard-tissue, the dentine causing its

special pathophysiology. Pathological processes of pulp are based on the

changes of blood-flow. Vitalmicroscopic method is an essential way of

examining such processes.

On the one hand it enables us to study the effect of different materials and

stimuli -applied on a very thin ( 20-40ľm) pulpal-wall - on blood-flow. On the

other hand it provides important data to identify the vascular reactions of pulp.

The direct examination of pulpal blood-flow is completed by using laser Doppler

flow-meter in teh experimental haemorrhagic hypotension induced. We wish to

carry out our examinations with the method we have been using for years.

a) local effect of L-NAME in the initial phase of pulpal-inflammation

b) the same experiment is planned to be carry out on pulp-vessels of diabetic

rats

c) to add a new type of advhesives to our previous examinations with dental_

adhesives

d) further examinations of tooth-neck varnishes/adhesives

e) to continue the vitalmicroscopic study of chemical components of adhesive

systems

f) to clarify the role of neurogenic inflammation (NO) on an electrically

stimulated model

g) to investigate the role of sensoric nerves by SP-antagonist on applied

bondmaterials

h) to compare the effectiveness of the two examination-methods applied

i) to investigate presence of autoregulation in rat's dental-pulp

coordinator: Ida NYARASDI